What does it mean if I test positive for HSV but IgG?

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What does it mean if I test positive for HSV but IgG?​

Test Results and Timing of Infection. If you test positive for HSV IgG but not IgM, then your herpes infection is probably not recent. You’ve probably been infected for at least two months. Individuals with newer infections are more likely to test positive for both herpes IgG and IgM.

What are the contraindications for HSV IgG testing?​

There are no contraindications for HSV IgG testing, and the risks associated with the procedure are very low. This test requires no preparation, and it only takes a few minutes. The minimum window period (the time between exposure and the production of detectable antibodies) for HSV is four to six weeks after the suspected exposure.
What is the DiaSorin liaison® HSV-1/HSV-2 type specific IgG assay?
The DiaSorin LIAISON® HSV-1 and HSV-2 Type Specific IgG assay is a chemiluminescent immunoassay (CLIA) technology used for the qualitative determination of specific IgG antibodies to Herpes simplex virus Type 1 (HSV-1) and Type 2 (HSV-2) in human serum. The test is performed on the LIAISON® XL Analyzer.

How is the herpes simplex IgG test performed?​

The Herpes Simplex IgG test is performed using an ELISA (Enzyme Linked Immunosorbent Assay) test kit manufactured by Euroimmun Diagnostics (Germany). This ELISA test provides a quantitative in vitro assay for human antibodies of the IgG class against HSV 1/2 (group specific) viruses in serum or plasma.

Does this test indicate the site of the HSV-1 virus infection?​

This test does not indicate the site of HSV infection. There is a considerable homology between HSV-1 and HSV-2 antigens, so that antibodies formed against either virus are highly cross-reactive. This assay is based on glycoprotein G-2, purified from HSV-2 infected cells, and is specific for type 2 antibodies.
How long does it take for HSV IgM antibody levels to decline?
By contrast, the HSV IgM antibodies reach detectable levels within seven to 10 days of exposure and start to decline after two weeks. As such, the HSV IgM test can be helpful in the diagnosis during acute infections.