What are the side effects of levothyroxine?

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What are the side effects of levothyroxine?​

When given in high doses, thyroid hormone preparations can cause mild serum enzyme elevations. In addition, standard doses of levothyroxine have been linked to rare instances of mild, immunoallergic liver injury. Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland.

What do we know about levothyroxine pharmacokinetics (PKS)?​

What do we know about levothyroxine pharmacokinetics (PKS)?
Generally, levothyroxine is used to treat thyroid hormone deficiency, and after a brief review of thyroid hormone physiology, this article will highlight what is known about the pharmacokinetics (PKs) of levothyroxine, as well as describe factors that can influence its PKs.

What is the therapeutic index of levothyroxine?​

Levothyroxine has a narrow therapeutic index and is titrated to maintain a euthyroid state with TSH (thyroid stimulating hormone) within a therapeutic range of 0.4–4.0 mIU/L.

Is levothyroxine the same as thyroxine?​

Is levothyroxine the same as thyroxine?
Levothyroxine is a synthetic levoisomer of thyroxine (T4), similar to the endogenous hormone produced by the thyroid gland. Thyroxine is de-iodinated to form triiodothyronine (T3) in the peripheral tissues.

Can levothyroxine be used to treat obesity?​

Thyroid hormone should not be used to treat obesity in patients with normal thyroid function. Levothyroxine is ineffective for weight reduction in normal thyroid patients and may cause serious or life-threatening toxicity, especially when taken with amphetamines.

What is the maximum dose of levothyroxine?​

What is the maximum dose of levothyroxine?
The maximum dose is 200 microgram daily. The dose in children is reduced according to other pre-existing conditions, weight and age. Elderly people or people with pre-existing health conditions usually need a smaller dose because they are more sensitive to the effects of levothyroxine.

 

[Yapay-Zeka]

Levothyroxine, a synthetic form of thyroxine hormone, is commonly used to treat thyroid hormone deficiency. However, like any medication, it can have side effects. Some of the side effects of levothyroxine include:

1. Mild serum enzyme elevations: When given in high doses, thyroid hormone preparations, including levothyroxine, can cause mild serum enzyme elevations. This is a potential side effect that may indicate liver strain.

2. Immunoallergic liver injury: Rare instances of mild immunoallergic liver injury have been linked to standard doses of levothyroxine. This is another possible side effect to be aware of, although it is not common.

It's important to note that most people tolerate levothyroxine well and experience minimal side effects. However, it's crucial to monitor for any adverse reactions and consult a healthcare provider if you experience any concerning symptoms while taking this medication.

If you have any further questions about the side effects or other aspects of levothyroxine, feel free to ask!