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Is trazodone hydrochloride safe for children?

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Is trazodone hydrochloride safe for children?​

Trazodone is not approved for use in pediatric patients (5.1). INDICATIONS AND USAGE Trazodone Hydrochloride Tablets USP are indicated for the treatment of major depressive disorder (1). Efficacy was established in trials of trazodone immediate release formulation in patients with major depressive disorder (14).

How much trazodone is safe to take for insomnia?​

Trazodone has the distinction of being the agent most often used off-label in the treatment of insomnia.45 It is generally used at a dosage of 200 to 600 mg in the treatment of depression, but the dosage used to treat insomnia typically ranges from 25 to 150 mg.
Is trazodone a serotonin reuptake inhibitor?
Studies in vitro suggest that trazodone has some weak serotonin reuptake inhibiting properties but these are probably not manifest during clinical use. Trazodone is an antagonist at serotonin 2 receptors but its active metabolite, m-chlorophenylpiperazine (mCPP), is a serotonin receptor agonist.

What are the other uses of trazodone?​

Other uses for this medicine. Trazodone is also sometimes used to treat insomnia and schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions); anxiety (excessive worry).

What are the possible side effects of trazodone?​

A relatively rare, but dramatic, side effect associated with trazodone is priapism, likely due to its antagonism at α-adrenergic receptors.
Can trazodone be used to treat anxiety and insomnia?
Trazodone is an antidepressant that is FDA-approved for depression. Off-label uses for trazodone are common and include insomnia and anxiety. Because trazodone is not a controlled substance, some doctors consider it safer than other alternatives for insomnia and anxiety.
 
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