Is naltrexone a MAT option for me?

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Is naltrexone a MAT option for me?​

Naltrexone is not a recommended MAT option for anyone younger than 18 years of age, or for patients experiencing other health conditions. Naltrexone is not an opioid, is not addictive, and does not cause withdrawal symptoms with stop of use. Naltrexone blocks the euphoric and sedative effects of opioids such as heroin, morphine, and codeine.

Is there abuse and diversion potential with naltrexone?​

Is there abuse and diversion potential with naltrexone?
There is no abuse and diversion potential with naltrexone. To reduce the risk of withdrawal symptoms, patients should wait at least 7 days after their last use of short-acting opioids and 10 to 14 days for long-acting opioids, before starting naltrexone.

Is naltrexone safe for a 16 year old?​

Naltrexone is not a recommended MAT option for anyone younger than 18 years of age, or for patients experiencing other health conditions. Naltrexone is not an opioid, is not addictive, and does not cause withdrawal symptoms with stop of use.

Is low-dose naltrexone available in the UK?​

Is low-dose naltrexone available in the UK?
Prescription and medical formulation of low-dose naltrexone in the UK are unlicensed in the treatment of multiple sclerosis.

What are the most common side effects of naltrexone?​

Serious side effects of naltrexone may include: Risk of opioid overdose. Accidental overdose can happen in two ways. Naltrexone blocks the effects of opioids, such as heroin or opioid pain medicines. Patients who try to overcome this blocking effect by taking large amounts of opioids may experience serious injury, coma, or death.

What is intramuscular extended release naltrexone used for?​

What is intramuscular extended release naltrexone used for?
Intramuscular extended release Naltrexone is a medication approved by the Food and Drug Administration (FDA) to treat both opioid use disorder (OUD) and alcohol use disorder (AUD) as a medication-assisted treatment (MAT) option.

 

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Naltrexone, a medication used in the treatment of opioid and alcohol use disorders, is generally not recommended for individuals under 18 years of age due to limited safety data in this age group. Additionally, individuals with certain health conditions may not be suitable candidates for naltrexone therapy. It is worth noting that naltrexone is not an opioid itself, is non-addictive, and does not lead to withdrawal symptoms upon discontinuation.

One of the key mechanisms of naltrexone is blocking the euphoric and sedative effects of opioids such as heroin, morphine, and codeine. Unlike some medications used in Medication-Assisted Treatment (MAT), naltrexone does not have abuse or diversion potential, as it does not produce a euphoric effect itself. To prevent the risk of withdrawal symptoms when starting naltrexone, it is generally recommended that patients wait at least 7 days after their last use of short-acting opioids and 10 to 14 days for long-acting opioids.

In the UK, the prescription and medical formulation of low-dose naltrexone for the treatment of conditions such as multiple sclerosis are unlicensed. This means that the use of low-dose naltrexone for this purpose is not approved by the regulatory authorities, and its safety and effectiveness for these conditions may not have been extensively studied or established.

When considering naltrexone therapy, it is important to be aware of potential side effects. While naltrexone is generally well-tolerated, some individuals may experience side effects. Serious side effects of naltrexone can include a risk of opioid overdose if a person attempts to override the blocking effects of opioids by taking large amounts of these substances, which can lead to severe consequences such as injury, coma, or even death.

Intramuscular extended-release naltrexone is an FDA-approved medication that is used to treat opioid use disorder (OUD) and alcohol use disorder (AUD) as part of medication-assisted treatment (MAT). This formulation provides a sustained release of naltrexone over an extended period, helping individuals manage cravings and reduce the rewarding effects of opioids or alcohol, thereby supporting recovery from substance use disorders.