How do you choose the right statin?

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How do you choose the right statin?​

STATIN SELECTION. The choice of statin therapy begins with the clinician’s preferred treatment approach, whether that is the ACC/AHA method of statin treatment groups or the AACE method of LDL-C or non–HDL-C goals. From there, properties of each statin must be taken into account to determine the best option for the individual patient.

What are the side effects of statins?​

Statins are not without risk. They can cause side effects like muscle pain, liver damage, increased blood sugar and neurologic symptoms such as memory loss and confusion. These side effects may be dose-related, with risks increasing at higher doses.
Do statins cause liver enzymes to be elevated?
Low to moderate doses of statins don’t appear to severely raise liver enzyme levels. Memory problems. Some people have reported memory loss and thinking problems after using statins. But a number of studies haven’t been able to find any evidence to prove that statins actually cause these difficulties.
What is the best selling statin drug in the world?
Statin. The best-selling statin is atorvastatin also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. The manufacturer Pfizer reported sales of US$ 12.4 billion in 2008. Due to patent expirations, several statins became available in 2016 as less expensive generics.

What is a statin drug?​

US Pharm. 2018;43 (7):22-26. ABSTRACT: Statins are a class of medications widely used for primary and secondary prevention of cardiovascular events. With six statins available generically, the selection of an appropriate agent may be determined based on drug-specific factors, including dosing considerations, drug interactions, and adverse events.

What are the side effects of statins for high cholesterol?​

Statin. Side effects of statins include muscle pain, increased risk of diabetes mellitus, and abnormalities in liver enzyme tests. Additionally, they have rare but severe adverse effects, particularly muscle damage. They inhibit the enzyme HMG-CoA reductase which plays a central role in the production of cholesterol.
How many different statins are available generically?
Considerations in the Approach to Appropriate Statin Selection 1 AVAILABILITY. Of the seven different statins on the market, six are available generically ( TABLE 1 ). 2 TREATMENT RECOMMENDATIONS. Several heavily debated treatment guidelines discuss the role of statins in treating hyperlipidemia. 3 STATIN SELECTION.

How many milligrams of statin are in a dose?
Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High-Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) 62 61 60 80mg ($9 gen, $ 236. br) 59 58 56 20 mg 54 ($196) 52

Are Statins safe to use?​

With a variety of generic options on the market and strong evidence backing their use, statins are some of the most widely prescribed medications in the world. 1 However, frequent use of these agents has led to continual scrutiny of their safety and ongoing debate about their role in therapy.

Are Statins safe for the elderly?​

Primary Prevention With Statins in the Elderly. This guideline cautions against “uncritical” initiation of statin therapy in those >60 years of age, even if the estimated risk is >10% 10-year risk for fatal CVD. However, they suggest statins should be considered in older adults with all four of the major risk factors.
What happens if you take too much statins?
However, too much ‘bad cholesterol’ (called low-density lipoprotein or LDL) is unhealthy. Statins reduce the amount of ‘bad cholesterol’ your body makes. High levels of ‘bad cholesterol’ in your blood can lead to fatty deposits building up in your arteries.